DES oncologie Toulouse

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Preoperative versus postoperative radiotherapy in soft-tissue sarcoma of the limbs: a randomised trial

Sarcomes - Publié le 18/11/2019 par Gauthier Glemarec

External-beam radiotherapy (delivered either preoperatively or postoperatively) is frequently used in local management of sarcomas in the soft tissue of limbs, but the two approaches differ substan... lire la suite

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Validated prediction of clinical outcome in sarcomas and multiple types of cancer on the basis of a gene expression signature related to genome complexity

Sarcomes - Publié le 18/11/2019 par Gauthier Glemarec

Sarcomas are heterogeneous and aggressive mesenchymal tumors. Histological grading has so far been the best predictor for metastasis-free survival, but it has several limitations, such as moderate re... lire la suite

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Effect of adjuvant therapy on the risk of recurrence in early-stage leiomyosarcoma: A meta-analysis

Sarcomes - Publié le 18/11/2019 par Gauthier Glemarec

To assess the effect of adjuvant chemotherapy (AC) or radiotherapy (AR) on the risk of recurrence in surgically treated patients with early-stage uterine leiomyosarcoma (uLMS).... lire la suite

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Histotype-tailored neoadjuvant chemotherapy versus standard chemotherapy in patients with high-risk soft-tissue sarcomas (ISG-STS 1001): an international, open-label, randomised, controlled, phase 3, multicentre trial

Sarcomes - Publié le 18/11/2019 par Gauthier Glemarec

Previous trials from our group suggested an overall survival benefit with five cycles of adjuvant full-dose epirubicin plus ifosfamide in localised high-risk soft-tissue sarcoma of the extremities or... lire la suite

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Survival impact of centralization and clinical guidelines for soft tissue sarcoma (A prospective and exhaustive populationbased cohort)

Sarcomes - Publié le 18/11/2019 par Gauthier Glemarec

The outcome of sarcoma has been suggested in retrospective and non-exhaustive studies to be better through management by a multidisciplinary team of experts and adherence to clinical practice guidel... lire la suite

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